Which viral infection is often associated with elevated liver enzymes and hepatomegaly?

The association of a viral infection with elevated liver enzymes and hepatomegaly is a key feature of hepatitis viruses in general. Hepatitis A virus (HAV) is primarily known for causing acute hepatitis, which can manifest with these symptoms, although it typically presents with a self-limiting course and rarely leads to chronic liver disease.

In the case of HAV, elevated liver enzymes indicate liver inflammation and damage, which is a common response to the viral infection. The liver is essential in processing and clearing the virus, leading to temporary alterations in function and size, manifesting as hepatomegaly.

Understanding the context of the other viruses helps clarify why HAV is the focus here. Hepatitis B virus (HBV) and hepatitis C virus (HCV) are also associated with elevated liver enzymes and hepatomegaly, but they tend to have a more significant risk of chronic liver disease, which can lead to more serious complications over time. Hepatitis D virus (HDV) typically occurs in conjunction with HBV and shares similar clinical features, but its impact is secondary to HBV infection.

In summary, while several hepatitis viruses can cause elevated liver enzymes and hepatomegaly, HAV is most notably associated with these features in the context of