What is a common complication of untreated peptic ulcers?

A common complication of untreated peptic ulcers is perforation, which refers to the development of a hole in the wall of the stomach or duodenum. When a peptic ulcer erodes through the gastrointestinal tract, it can lead to leakage of gastric contents into the abdominal cavity, resulting in a serious condition known as peritonitis. This condition can cause severe abdominal pain, fever, and systemic infection, requiring immediate medical intervention, often surgical repair.

This complication emphasizes the importance of prompt diagnosis and treatment of peptic ulcers to prevent severe outcomes. In contrast, the other options listed do not directly stem from unresolved peptic ulcers. For instance, leukemia and chronic fatigue syndrome are not associated with the digestive system, while pancreatitis is related to inflammation of the pancreas and can have various causes, none of which are direct complications of peptic ulcers. Therefore, perforation is a critical complication linked to peptic ulcers that must be recognized and managed appropriately.